Extração de taninos da casca de barbatimão [Stryphnodendron adstringens (mar.) coville] e sua aplicação na formulação de cremes com potencial cicatrizante

Abstract

In wound healing processes, burns and inflammations, the tannins help to form a protective layer of complex tannin-protein and / or polysaccharide on lesioned epithelial tissues, being able to, just below this layer, the curative process occurs naturally, therefore, it becomes interesting To study barbatimão bark tannin extraction, since these are known to have healing effects and, applied in the formulation of creams, and can be used as auxiliaries in healing treatments of cutaneous wounds. The barbatimão shells were taken from a specimen of the species in the Brazilian native cerrado. The extraction of tannins occurred by heating, under reflux, the pulverized hulls. The total and condensed tannins were identified according to the described methodology, where the presence of precipitates in the extract samples was observed. The plant sample was submitted to purity verification tests such as determination of foreign matter, determination of moisture content, total ash and acid insoluble, all the tests presented conformities within the standards listed by the pharmacopoeia. The cream with healing potential was formulated containing its distinct concentrations of barbatimão extract. The formulation underwent pH correction and centrifugation tests and cycle freezes in order to determine its stability, the results of the same demonstrated compliance. Based on these results, the formulated cream has favorable characteristics for topical application with the potential to assist in the healing of cutaneous wounds.